Differential Centrifugal Sedimentation Particle Size Analysis

Differential Centrifugal Sedimentation (DCS) analysis of particle size to generate robust data for small sample volumes

Differential Centrifugal Sedimentation (DCS) particle size analysis from our experts provides high resolution results which applies to a wide variety of samples, some of which can present unique difficulties for other particle sizing methods. 

Particle sizing can present costly and time-consuming challenges, with further concerns residing in the accuracy of reporting of particle size distribution.

In contrast with other particle size techniques – such as laser diffraction - our CPS Disc Centrifuge is accurate and versatile with a large dynamic range and has a rapid detector response, operating with an effective response time (to 95% accuracy) of ~0.1 second, while competitive sedimentation instruments have a response time of ~1 to 4 seconds, used for a wide range of particle sizing, between  >0.002um – 50um dependent on particle density.

Our centrifuge operates at up to 24,000 RPM, which transpires that analyses of very small particles is three times faster than other centrifuges. Analyses of samples with very wide size ranges can be completed rapidly through the use of centrifuge speed ramping, and any analyses that are potentially impractically long (several hours or more) can be completed rapidly.

Applications include analysis of polymer latexes and emulsions, fillers, ceramic oxides, abrasives (of all types), inkjet inks, pigments, microspheres, oil emulsions and much more. Many materials - such as oil emulsions, wax emulsions, adhesive latexes, and liposomes - that may have presented difficulties for measurement via differential sedimentation can now be measured quickly and with very high resolution: previously, differential sedimentation has historically been limited to particles more dense than the fluid in which they are suspended. 

DCS uses a technique wherein the sample is delivered to the bottom of the centrifuge chamber, rather than to the fluid surface. This method allows particles that are lower in density than the fluid to float toward the fluid surface. Neutrally buoyant particles in water (density ~1.0 g/ml) can be measured by conducting the analysis in deuterium oxide (density 1.108 g/ml)

Contact one of our experts to discuss your requirements in regard to particle sizing by DCS.